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Trimethyl phosphite is one of those chemicals that quietly sits behind a lot of industrial work. It’s a clear liquid, slightly sharp in smell, and used in several reactions where precision really matters. Because of that the Government has placed it under the Compulsory Registration Scheme (CRS) of BIS. The standard you need to follow here is IS 17412:2020, which talks only about the technical-grade material
The rule basically says: if you want to make it, import it, or sell it in India, you must have the BIS registration in place. No exceptions on that part.
Trimethyl phosphite works like a building block in many chemical processes. Companies use it for organic synthesis, for preparing other phosphorus-based chemicals, and sometimes as a reagent in special reactions.
Because of its role, the product cannot be sold casually. Slight variation in purity can completely change the reaction output. That’s why BIS wants everyone to follow the same quality line.
The standard lays down what “technical grade” should actually mean. It does not go into fancy details, but it clearly mentions:
These things help keep the quality consistent. Even if two companies manufacture it in different ways, the final product must match the same benchmark.
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The Quality Control Order made this product a notified chemical. Once a chemical gets listed under a QCO, the BIS registration becomes compulsory. It is done mainly to avoid unsafe or poor-grade chemicals entering industrial supply chains.
So, what does it mean for businesses?
For most companies this is now a routine requirement but many still get caught off-guard because of documentation issues
Any company that manufactures or intends to supply trimethyl phosphite in India needs the registration. This includes:
One thing many people don’t know is that BIS gives the licence only to the manufacturer. Importers can file the application, but the final approval stays in the manufacturer’s name.
Before filing the CRS application, a few things must be lined up. Missing even one usually causes delays:
The manufacturer must show factory registration, production capability, and basic business documents. BIS wants to verify that the product is genuinely being produced at the stated location.
Technical data sheets, manufacturing process notes, and any company-specific specification documents.
These help BIS confirm that the product falls under IS 17412:2020.
If the product carries a brand name, proof of ownership or authorization is needed. BIS won’t approve an unverified brand.
Foreign manufacturers must appoint an AIR in India. The AIR handles communication, document submission, and local responsibilities.
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The steps feel lengthy when written in detail, but in practical terms, the process moves like this:
For Indian manufacturers
For foreign manufacturers
The lab checks the chemical to see if it actually matches the product description given in IS 17412:2020
Common checks include:
If the sample fails even one essential parameter, the manufacturer must correct the batch and submit fresh samples.
A few small oversights cause most rejections. Some examples include:
These are easy to avoid, but companies often miss them because the process feels repetitive.
Operating without registration can lead to:
Trimethyl phosphite is currently controlled closely in India and any enterprise that handles it must comply with the IS 17412:2020 in the scheme of BIS CRS. It is very easy when the documents are ready, however, precision counts. Get in touch with Agile Regulatory for expert help.
When intending to manufacture or deliver this chemical in India then you should better start the compliance procedures. BIS grants applications when all is clean, consistent and tested properly.
Nishi Chawla
02 Feb, 2026
Nishi Chawla
02 Feb, 2026
Nishi Chawla
02 Feb, 2026
Vanshika Mathur
31 Jan, 2026
Divya Saxena
31 Jan, 2026
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